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Dissecting active ingredients of Chinese medicine by content-weighted ingredient-target network

Pryor JP, Ralph DJ

The SCFAs butyrate and propionate interact predominantly with HDACs 1 and 2, which are located in the nucleus, in addition to HDACs 3, 4, 5, 6, 7, and 9, which are shuttled between the cytoplasm and the nucleus (159)

2.5 Environmental and behavioral factors Environmental and behavioral factors that are linked to feline obesity include eating habits, feeding schedules, indoor house confinement, and sedentary nature (21, 30, 31)