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The liberated N-terminal fragment of GSDMD (GSDMD-N) oligomerizes within the plasma membrane to form pores, leading to pyroptotic cell death 52

N -methyl-nicotinamide, a reaction side product of NNMT, is a specific and potent inhibitor towards NNMT

The influence of UA levels on the progression of oxidative stress and neuroinflammation at different stages of neurodegenerative diseases requires further investigation

A GST mutant in which four glutamine residues were replaced with asparagine (GST 4QN ) exhibited a glutathione binding affinity similar to that of wild-type GST and could be purified by glutathione affinity chromatography

Moreover, HSP synthesis has shown to be dependent on adequate concentrations of glutamine [93]

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