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& Fiotakis, C

Thus, observed potent induction of ferroptosis, GPX4-dependent novel suppression of mTOR pathway and DNA damage repair response in preclinical in vitro model of TC supports GPX4 targeting for therapeutic benefit in advanced therapy-resistant thyroid cancers

These distinct RCD subroutines, such as apoptosis, autophagy, pyroptosis, cuproptosis, and ferroptosis, exhibit unique characteristics and displaying significant overlap and crosstalk [71]