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8 severe liver disease related outcomes were reported in median 3.8 years of follow up

We thus modified CspZ by conjugating it to bacteriophage Q-derived VLP, combined with eliminating its FH-binding activity to test whether this modified CspZ could be an effective vaccine of Lyme disease

meningitidis genome is characterized by an abundance of homopolymeric DNA repeats (simple sequence DNA repeats, SSRs) that undergo stochastic and reversible mutations (insertion/deletion) at a high frequency by slipped-strand mispairing during DNA synthesis associated with DNA replication or recombination (Saunders et al., 2000

Activated microglia release reactive oxygen and nitrogen species, pro-inflammatory cytokines, and other neurotoxic mediators that exacerbate oxidative stress and mitochondrial damage

Transdermal delivery can be used to bypass the first-pass effect, which would otherwise prematurely metabolize the drugs