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Keywords: anticancer potency, nanoparticles, cytotoxicity, docking analysis Introduction Nearly around 19.3 million new cases of cancer along with 10 million cancer-related deaths have been reported by the GLOBOCAN figures for 2020.1 Moreover, it is also being predicted that cancer will soon eclipse cardiovascular diseases as the leading cause of death.2 According to these estimates, female breast cancer has overtaken lung cancer (11.7% vs 11.4% of all cases) as being the most commonly diagnosed cancer worldwide.1 Many drugs as well as drug combinations with potent toxicity against cancerous cells have been developed for chemotherapy

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[] Administering the H3K9 methyltransferase inhibitor chaetocin reversed H3K9me3 enrichment at these loci, restored mitochondrial gene expression and function, improved cardiac systolic performance, and prolonged survival without affecting hypertrophy development

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