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One portal tract reveals bile ducts surrounded by concentric fibrosis ( Figure 3 )

Among the various regulated cell death (RCD) pathways, a novel formcuproptosishas recently emerged, uniquely triggered by disruptions in copper metabolism [2]

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A previous report suggested that a reduction in body weight of TAA-treated rats might be due, in part, to gastrointestinal toxicity and the concomitant loss of the animals appetite with subsequent reduction in food intake or the excessive loss of water, salts, and proteins as a result of renal injury, resulting in dehydration and weight loss 21