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A number of studies have evaluated B12, folic acid, and B6 as part of homocysteine-lowering therapy

It can lead you towards excessive weight gain

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While anyone can develop B12 deficiency, certain groups are more vulnerable: Vegetarians and vegans Adults over 50 Individuals with gastrointestinal disorders People taking long-term acid-reducing medications Those who have undergone gastric surgery According to the National Center for Biotechnology Information, vitamin B12 deficiency can result from both dietary insufficiency and impaired absorption, particularly in individuals with underlying gastrointestinal conditions

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Out-of-spec pH (too acidic or too alkaline) accelerates hydrolysis of Asp-Pro and Asp-Gly bonds