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Throughout the stages of aging, cells begin to lose their ability to repair themselves and produce strong antioxidants

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J Appl Physiol 54 : 147151

The biomarker approach requires analytical evaluation of (poly)phenol metabolites in biofluids to essentially reverse-trace a (poly)phenol from its end-stage metabolites towards its precursor and subsequently to its sources in food (Reference Scalbert, Brennan and Manach19)