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Regulation of T-cell tolerance by lymphatic endothelial cells

Oxidized DNA base lesions are mainly removed by two types of pathways: base excision repair (BER), involving the removal of single lesions by a glycosylase action, and NER, which is a more complex process involving the removal of a lesion containing oligonucleotides [51]

Kamerbeek NM, van Zwieten R, de Boer M, Morren G, Vuil H, Bannink N, Lincke C, Dolman KM, Becker K, Schirmer RH, et al

Moreover, distinct homeostatic control mechanisms regulate FoB and MZB distribution in the spleen 15,16

This creates a relentless cycle of inflammation and oxidative stress, perpetuating a hostile microenvironment that damages normal epithelial and stromal cells over time

To further explore the differences seen between ME/CFS and long COVID patients, we identified significant predictors of treatment effectiveness, i.e., the NAS, from disease diagnosis (ME/CFS vs