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Initially, the alterations in intracellular protein concentrations post-treatment were assessed, and the principal component analysis (PCA) outcomes demonstrated a notable divergence in protein expression between the D-CuP-treated group and the PBS-treated control group (Fig

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In addition to the collected metabolic findings, four studies found that IF could reduce blood pressure levels (10, 23, 24, 26)

As already discussed, eNOS uncoupling, due to the various uremic toxins, including asymmetric dimethyl-arginine, is a ROS contributor to oxidative stress and ROS-derived damage in the kidney (Ueda et al