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The current state of ongoing clinical trials states that treatment of aducanumab has so far proven beneficial

Molecular structures of siRNA are subjected to chemical modifications, such as the addition of 2-O-methyl or 2-fluoro replacements (106), in order to enhance their stability and reduce the occurrence of off-target effects, while simultaneously enhancing transport efficiency and limiting adverse effects

J Child Neurol 19:413417 Paca SP, Neme B, Vlase L, Gagyi CE, Dronca E, Miu AC, Dronca M (2006) High levels of homocysteine and low serum paraoxonase 1 arylesterase activity in children with autism

doi: 10.1038/s41598-019-42693-x 47

Which brings us to our second angle of attack against DHT Angle Of Attack #2: Reducing 5-Alpha Reductase There seems to be at least two pathways to inhibiting (or reducing the presence of) this enzyme