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J Pharm Pharm Sci 27:13062

260 This imbalance of oxidation and antioxidation will further aggravate the accumulation of ROS

Through structural optimization, the orally administered inhibitor DFV890 achieves colon-specific release, suppressesing ASC oligomerization and IL-1 maturation in diabetic lung injury models

D 66 , 486501 (2010)

et al., 2020), prostate cancer (Qin et al., 2021), breast cancer (Yang J

Even though GSH levels were below the threshold for rescuing WT cell growth in cystine-free conditions, co-culturing with GGT1 + cells led to complete rescue of WT cell growth (Fig