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[31] Under a similar scope Lukaszuk et al produced compound AL-11 , which was able to inhibit IRAP ( K i = 27.5 nM) and displayed around 200-fold selectivity over APN

The combination offers hope for patients who've plateaued on GLP-1s alone or need maximum weight loss

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Injection site reactions : The most common side effects are mild and short-lived, including soreness, redness, or slight swelling at the injection site