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Hurley JD

doi: 10.1038/nrdp.2015.35 503 ZeuthenLHFinkLNFrokiaerH

What are clinicians observing

Procedures like chemical facial peels, intense pulsed light treatment and microdermabrasion can damage melanocytes and stimulate excess pigmentation

BCL-2/adenovirus E1B 19KD interacting protein 3 (BNIP3) protein is an effective inducer of cell death and autophagy, causing a protective stress response to remove damaged mitochondria (Hamacher-Brady et al., 2007)