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While AOD9604 has not achieved the commercial success initially envisioned, it has contributed valuable insights into the dissociable functions of different regions of the growth hormone molecule and has validated the concept that targeted metabolic effects can be achieved without unwanted growth hormone receptor activation

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Mientras que NMN y NR aportan sustratos que las clulas convierten en NAD+ por vas de rescate, 5-Amino-1MQ acta en sentido inverso: en lugar de aadir material de construccin, inhibe la NNMT, la enzima que consume nicotinamida y drena indirectamente el pool de NAD+

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