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This is a concern that applies to all significant weight loss interventions, not just tirzepatide, but it becomes more relevant as the magnitude of weight loss increases

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Blood donation (including whole blood as well as plasma, platelets, leukocytes or stem cells by apheresis) is permitted provided it is performed at a collection center accredited by the relevant national regulatory authority

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Glutathione participates in cellular maintenance processes related to oxidative balance and metabolic wellness