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Immunohistochemistry analysis revealed that Sorafenib treatment significantly reduced the levels of SLC7A11 and Ki67, a proliferation marker, and increased the level of 4-HNE, a marker of ferroptosis, in tumor tissues (Fig

Although many synthetic photoprotective compounds are available, they have potential toxicity, mainly due to ROS induction in human skin (346)

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Consequently, with the lack of gastric intrinsic factor, IFmediated active absorption in the ileum is compromised

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This damage accumulates as oxidative stress, a chemical imbalance that affects energy levels, skin clarity, and immune resilience