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The RNA samples (1 ng) were reverse transcribed into cDNA using the Hiscript III Reverse Transcriptase Kit (Vazyme, R223-01)

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Semaglutide directly stimulates GLP-1 receptors in the brain, decreasing appetite and changing satiety signals, and has a prolonged half-life of approximately seven days, enabling once-weekly administration

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J Neurol 2022 Correll CU et al

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