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doi:10.1016/S0140-6736(23)01053-X PubMed: This trial evaluated retatrutide in 281 participants with type 2 diabetes, showing up to 16.94% weight loss and significant HbA1c reductions with favorable safety profile comparable to other GLP-1 based therapies

Front Biosci (Elite Ed)

By comprehensively analyzing the findings in this field, it is obvious that different AA metabolites and pathway factors correlate with and play distinct roles in response to different exogenous stimuli in cardiovascular and metabolic systems via specific cellular mechanistic events

Indeed we have demonstrated this in models of IC/BPS

Mater 19 (19), 581593

By in-depth analysis of the advantages and challenges faced by the multi-target intervention of natural products, this review is expected to provide a new perspective for in-depth understanding of the complex pathophysiology of PH, and offer theoretical basis and ideas for the development of new therapeutic strategies based on natural products, which are intended to reverse immune-metabolic imbalance and vascular remodeling