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Rapid Discovery of CD38 Inhibitor via DNA Encoded Natural Product Library Screening Anti CD38 antibody therapy for patients with relapsed refractory multiple myeloma: differential mechanisms of action and recent clinical trial outcomes Annals of Hematology Springer Nature Link 5 Amino 1MQ blocks an enzyme called NNMT, and the mechanism is real, but NNMT overexpression does not track body fat. It tracks insulin resistance. Non diabetic individuals at BMI 33 had normal NNMT. And Selective and membrane permeable small molecule inhibitors of nicotinamide N methyltransferase reverse high fat diet induced obesity in mice PMC Nicotinamide N Methyltransferase (NNMT) and Liver Cancer: From Metabolic Networks to Therapeutic Targets Monoclonal anti CD38 therapy in human myeloma: retrospects and prospects Frontiers

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