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This review explores the core mechanisms of ferroptosis and its role in CNS diseases, including acute injuries (e.g., IS, CIRI, ICH, SAH, TBI, and SCI) and NDDs (e.g., AD, PD, HD)

Przeprowadzono pojedyncze badania z wykorzystaniem glutationu na komrkach raka jajnika, w ktrych wykazano zwikszenie wraliwoci komrek na leczenie przeciwnowotworowe

Although BAs can regulate ferroptosis-related molecules via FXR activation and Lactobacillus metabolites possess Nrf2 activation potential, direct experimental evidence for their effects in PCOS ovarian granulosa cells is still lacking

In DSS-induced colitis, mice that were fed experimental diets containing AST (100200 ppm) exhibited lowered gene expressions of several inflammatory markers including TNF-, IL-1, IL-6, COX-2, and iNOS and inhibited NF-B expression in the colon [43]

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Conclusions Currently, research data show that H2O2 can play a dual role in cells