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FIGURE 3 A high concentration of Se compounds also performs a redox-active act as prooxidants, generating ROS in reaction (Table 1), SeMet could inhibit cell proliferation by inducing ROS generation and activating apoptosis cellular proteins, including the caspase family and p53 ( 2 downregulated Bcl-2 survival genes in lung cancer cell lines ( The current research on Se compounds focuses on both sides of the spectrum: the protective effect against cell damage or the anti-proliferation effect against cancer cell lines

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Accessed August 23, 2025