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The potentially beneficial features of IgE include its affinity for the FcR, expressed by the immune effectors responsible for ADCC and ADCP, and the low levels of normal IgE in the blood, which avoids competition with the therapeutic IgE

However, it is possible to get sufficient B12 on a vegan diet when properly educated in vegan B12 sources

Figure 9 In summary, through their customizable design, COF platforms not only overcome key limitations of conventional sensitizers-such as insufficient ROS generation, limited tissue penetration, and poor targeting-but also advance therapeutic paradigms from simple cell ablation to precisely inducing layered, immunogenic forms of cell death

doi: 10.1667/RR13837.1 75 SuzukiFLoucasBDItoIAsaiASuzukiSKobayashiM

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Thanks to the Vegan Society for allowing us to link to their website: Devalia V et al (2014) Guidelines for the diagnosis and treatment of cobalamin and folate disorders [Accessed 29.11.19] Linnebank et al (2011) Antiepileptic drugs interact with folate and vitamin B12 serum levels [Accessed 22.10.19] Sukumar and Saravanan (2019) Investigating Vitamin B12 deficiency [Accessed 29.11.19]