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In rat permanent MCA occlusion, infusion of ebselen, starting 45 min before and maintained 4 h after the occlusion, reduced cerebral cortical damage by 28%

Conversely, when oxidative challenges exceed physiological levels, they can disrupt redox signaling and cause oxidative damage to biomolecules, termed oxidative distress

A 107 , 92089220 (2003) Rignanese, G., Angelis, F.D., Melchionna, S., Vita, A.D.: Glutathione transferase: a first-principles study of the active site

4.2.4 Donor cell developmental stage Although fetal cells remain the most established donor source in the field, factors such as their topographic origin, developmental stage, and biological sex, must be carefully considered, as each can significantly influence how the transplanted neurons integrate into the host environment

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M.KitteringhamN.et al