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demonstrated that H3K79me was involved in metformin-regulated mitochondrial biogenesis and senescence in age-associated vascular dysfunction [136]

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Prognostic impact of discordance in hormone receptor status between primary and recurrent sites in patients with recurrent breast cancer

The suggestion that reduced nuclear environment could protect oxidant sensitive proteins from oxidation [50] could be confirmed by our results: there was less glutathionilated and more oxidised proteins when the nuclear GSH was depleted by DEM (Fig