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Too much NRF2 activity is associated with uncontrolled proliferation and neoplasia

[PubMed] 86: Stein JD1, Newman-Casey PA, Kim DD, Nwanyanwu KH, Johnson MW, Hutton DW

As mentioned, the specific issue could be a strong effect on increasing angiogenesis, increased VEGF, increased egr-1 gene, increased NO, or eNOS stimulation and counteraction of increased free radical formation

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Moreover, our data demonstrate that the activity of CAT was upregulated, especially in WCM and 100 mM NaCl + WCM

Mol Psychiatry 29(8):25712574 Mandal PK et al (2022) Schizophrenia, bipolar and major depressive disorders: overview of clinical features, neurotransmitter alterations, pharmacological interventions, and impact of oxidative stress in the disease process