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Strengths and limitations The strengths of our study are as follows: (1) We performed a robust, streamlined proteomics method to quantify proteins in the human serum using nano UHPLC-MS/MS 15

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firstly found that p53 inhibited the uptake of cystine by blocking SLC7A11, which caused a significant reduction of GSH, and induction of cell ferroptosis (Xie et al., 2017)

Glossary Vitamin B-12 (Methylcobalamin & Cyanocobalamin): Active form of B-12 which supports metabolism, aids in the production of red blood cells, protects nerves, improves brain function, reduces fatigue, increases energy & alleviates depression and anxiety

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