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Just last year, the FDA issued a recall of 27 over-the-counter eye drop products due to the risk of infections that could cause partial vision loss and even blindness

Specifically, GA significantly increased the expression of PGC1 target genes such as mitochondrial transcription factor A, nuclear respiratory factor-1, and nuclear respiratory factor-2, thereby upregulating fatty acid -oxidation enzymes like carnitine palmitoyltransferase-I, and promoting fatty acid oxidative metabolism in mitochondria (Doan et al., 2015)

Ziprasidone suppresses pancreatic adenocarcinoma cell proliferation by targeting GOT1 to trigger glutamine metabolism reprogramming

Furthermore, we found that the activity of ERK1/2 was negatively regulated by AMPK in vitro

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