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On the other hand, overexpression of Nrf2 (transcriptional regulator of seleno-GPxs) contributed to the increase in the radioresistance and stemness in glioma stem cells (GSCs) by upregulating GPx1 and decreasing the cellular ROS level

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Disclosure of interest: Nothing to disclose E-Posters - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.02 - ACUTE MANAGEMENT - Thrombolysis or thrombectomy P2078 - ESOC25-1486 OUTCOMES AFTER REPERFUSION THERAPIES IN PATIENTS WITH TANDEM OCCLUSIONS Felicia Glavan 1,2 , Natalia Ciobanu 1,2 , Danu Glavan 1,2 , Andrei Filioglo 1 , Diana Manea *1 , Roman Smolnitchi 1 , Stanislav Groppa 1,2 1 Institute of Emergency Medicine, Chiinu, Moldova, 2 Nicolae Testemitanu State University of Medicine and Pharmacy, Chisinu, Moldova Background and Aims: Tandem occlusions (TO) involving the extracranial internal carotid artery (ICA) and various intracranial arteries account for 13-30% of all large vessel occlusions (LVO)

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Studies indicate the potential alleviation of neuropathy symptoms through B vitamins, although trials face limitations, particularly in non-diabetic cases where pre-treatment vitamin levels are examined

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