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Copper is an integral part or cofactor for various proteins, also known as oxidoreductases, that participate in essential biological processes, including superoxide dismutases (SODs), cytochrome c oxidase, L-ascorbate oxidase, ceruloplasmin, and other enzymes (Jomova et al., 2024[221])

N-Acetyl L-Tyrosine (NALT) vs

Human Trx and GSH systems have compensatory activities so that inhibition of one arm can be supplemented by the other 60 , suggesting that the inhibition of hTrxR by some of the compounds presented here will not be detrimental for humans as it is for schistosomes

For the MTT assay, superoxide dismutase (SOD) activity measurement and determination of H 2 O 2 and NO concentrations, a 96-well plate with a fixed plasma flame was utilized