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The 40 group also showed a significantly better overall survival ( P =0.04)

In the pig LR3 IGF-1 study, plasma endogenous IGF-1 was suppressed during infusion (Tomas et al., 1997), and the guinea pig study showed reduced plasma IGF-I and IGF-II during LR3 administration (Bastian et al., 1995)

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When used in combination, these compounds support exploration of convergent secretagogue signalling, receptor crosstalk, and dualpathway regulatory responses under controlled laboratory conditions