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The exact magnitude varies widely, from modest improvements to dramatic transformations depending on starting point and adherence

Pretreatment evaluation included the following factors: complete medical history, assessment of ECOG-PS, chest X-rays, computed tomography (CT) of the chest to the pelvis, magnetic resonance imaging of the brain, and whole-body bone scintigraphy or 18-fluorodeoxyglucose on Positron Emission Tomography-CT

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Taking into consideration a thorough history and clinical manifestations is therefore paramount

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