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In a randomised, placebo-controlled study comparing the effects of erdosteine and NAC treatment for 10 days in 30 patients with mild-to-moderate COPD who were current smokers, both erdosteine and NAC caused significant reductions in ROS blood levels, but only erdosteine lowered 8-isoprostane levels and restored the short-term FEV 1 response to salbutamol [64]

Primary AML samples were obtained by bone marrow puncture or venipuncture during routine investigations at the time of diagnosis

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