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Copper-transporting P-type adenosine triphosphatase (ATP7B) as a cisplatin based chemoresistance marker in ovarian carcinoma: comparative analysis with expression of MDR1, MRP1, MRP2, LRP and BCRP

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The mechanism may be that CB-839 and AC220 synergistically deplete glutathione, induce the production of mitochondrial ROS, and lead to apoptosis

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