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Polylactic acid implants (New-Fill) to correct facial lipoatrophy in HIV-infected patients: results of the open-label study VEGA

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The distinction between IM and subcutaneous is unlikely to be clinically meaningful given the absence of human pharmacokinetic benchmarks for either route

IM bioavailability in rats 14-19%, dogs 45-51%

Exp Biol Med 241:972