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Xue-Jie-San prevents the early development of colitis-associated intestinal fibrosis by blocking Notch1 and FGL1 signaling pathways

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304 Studies have shown that hordenine decreases the expression of proinflammatory cytokines by suppressing the S1P/S1PR1/STAT3 pathway and promotes the healing of colonic ulcers by regulating the expression of tight junction proteins, including occludin and ZO-1

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