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This finding was further corroborated by liver-specific IRE1 knockout, which exacerbates liver fibrosis and inflammation in high-fat diet-induced mice [43]

The dilution curve gradually flattened out (Figure 6D) and the data were reasonable

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The assay uses two chemicals, 6 hydroxydopamine (6HD) and diethylenetriaminepentaacetic acid (DETAPAC), to generate anions, which are reduced in the presence of SOD

In brief, a unit of TMT reagent was thawed and reconstituted in acetonitrile (113212, Merck, USA)