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In particular, we noted significantly lower histological fibrosis scores, coupled with reduced collagen accumulation and expression of fibrotic genes and myofibroblast markers in the lung (Fig

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Although this approach showed promising ideas, the authors pointed out that kidney organoids in general resembled a rather immature form of the kidney and the Gb3 deposition with subsequent tissue damage in the patient takes a much longer time than the 3-week cultivation of these in vitro models

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doi: 10.3389/fmicb.2021.641251 Received 13 December 2020 Accepted 15 February 2021 Published 09 April 2021 Volume 12 - 2021 Edited by Kian Mau Goh, University of Technology Malaysia, Malaysia Reviewed by Taowei Yang, Jiangnan University, China