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10.1016/j.ceca.2009.12.003 245 SvenssonE.BeiskeA

Autoimmunity 2023;56:2290357

Under normal conditions, Keap1 complex-mediated ubiquitination degrades Nrf2, and when confronted with oxidative stress, Keap1 complex activity is inhibited and the Nrf2/ARE pathway is activated