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In 2019, Bersuker et al

There is evidence that SOD2s levels to be regulated by MAPK activity in vitro [74, 75], also substances such as anthocyanins, polyphenols, alkaloids, and phytoalexins, are responsible for the induction of SOD2 mRNA expression

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doi: 10.3969/j.issn.1671-4695.2020.19.009 33 CuiXJiangXZhangYLiLRanTBiXet al

62 However, in a phase II randomized controlled trial, SAM neither reduced liver damage in patients with HCV cirrhosis nor improved the liver function