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Despite all the beneficial effects, the detrimental effect of G6PD deficiency are still clear in hemolytic anemia and kernicterus of infancy

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In addition, cotreatment of docetaxel-resistant NSCLC with docetaxel plus R162 inhibited cancer cell growth and metastasis both in vitro and in xenograft mouse models, again suggesting that combination therapy with anticancer drugs plus a GLUD1 inhibitor is an effective cancer treatment 23

TNF alpha potentiates glutamate neurotoxicity by inhibiting glutamate uptake in organotypic brain slice cultures: neuroprotection by NF kappa B inhibition

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A study involving 240 individuals with prediabetes over nine months revealed that curcumin supplementation significantly reduced their risk of developing diabetes (480)