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Caution is advised regarding the use of oral supplements in patients with pernicious anaemia, meaning that careful monitoring of symptoms would be required, and is not generally advised in patients with neurological symptoms, owing to limited efficacy and potentially serious impact of permanent neurological damage[25]

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Excessive or prolonged inflammation damages healthy tissue and delays repair

Deficiency is linked to cognitive decline and dementia risk

Some preliminary studies suggest it can reduce oxidative stress markers and regulate inflammatory pathways

Find out more about these options and the research that backs them below