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Xi et al., 2022)

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NPs provide a targeted and efficient delivery system for these therapeutic genes, ensuring they reach the affected neurons in the brain

Although hyper-O-GlcNAcylation of insulin receptor substrate 1 and AKT serine/threonine kinase 2 inhibits their phosphorylation and induces insulin resistance in peripheral cells [70], the corresponding regulation of endocrine and exocrine secretion from the pancreas remains unclear

Expression of the CHRNA7 gene and its receptor product, the 7-nicotinic receptor (among other receptors), are significantly reduced in specific disorders, especially in ASD or schizophrenia [103]