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At present, the end-stage surgical treatment for IDD is interbody fusion, which often limits lumbar motion and may cause other complications, such as accelerating the degeneration of adjacent lumbar segments

- elevated folate levels - evidence indicates elevated folate levels diminish cognitive function therefore advisable to review necessity for its continued prescription

10.1016/j.tranon.2022.101364 124 SanchezC.El Hajj DiabD.ConnordV.ClercP.MeunierE.PipyB.et al (2014)

The Gly2019Ser, the most common among LRRK2 pathogenic variants, localizing in the kinase domain of the protein, accounts for 4 % of familial and 1 % of sporadic PD worldwide (Tolosa et al

The WT-based dosing strategy showed a higher risk of SOS than the age-based dosing strategy in 916 kg patients

Nabil Salama A, Badr EAE, Holah NS, El Barbary AA, Hessien M