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Generation of iPSC-derived kidney organoids recapitulating human Fabry nephropathy To generate Fabry kidney organoids, GLA-mutant human iPSCs were differentiated into kidney organoids using an adherent cell culture protocol 15,16

Photostability evaluation To test the photostability in buffer and cell culture media, PLGA nanoparticles encapsulating DDA-GSH-AuNCs in water (2 mg/mL) was mixed with water (control), PBS or DMEM that contains 10% FBS (final concentration of PLGA nanoparticles is 0.5 mg/mL and AuNCs 4 g/mL as gold)

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