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For those with risk factors like kidney disease, liver failure, or high blood pressure, long-term medication use can also present specific dangers

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While standard GLP-1s can sometimes cause lethargy due to reduced caloric intake, Tesofensine actively increases metabolic rate and often improves patient energy levels and focus

The Nat Geo article is not peer reviewed itself, but the studies mentioned within it are, except where it specifically identifies them as preprints

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