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The treatment with RSL3 (GPX4i) revealed a marked increase in ferroptotic sensitivity in CSFmax compared to Plasmax, an eaect that was rescued by the ferroptosis inhibitor Ferrostatin-1 ( Figure 3F , Sup

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These findings, along with the broad suppressive effects of Phe, Met, and Leu, align with the emerging role of single amino acid utilization by different bacterial species and strains in colonization, host range, and virulence (35, 38, 46, 56, 57)

However, the gradual correction of anemia takes place over a period of 90 days

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