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Patients at increased risk may be prescribed opioids such as hydrocodone bitartrate and acetaminophen tablets, but use in such patients necessitates intensive counseling about the risks and proper use of hydrocodone bitartrate and acetaminophen tablets along with frequent reevaluation for signs of addiction, abuse, and misuse

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However, the representation of hot-spot mutants within the variant library was not particularly enriched in either the SKOV3 or OVCAR5 cell lines (Supplementary Fig