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Of interest, although liver-derived IGF-I has endocrine effects on extrahepatic tissues, there are only few data regarding local effects of this hormone in the liver[87] probably due to the very low amount of IGF-I receptors on the hepatocytes membrane[46, 88, 89]

Crude extracts from Lycium barbarum suppress SREBP-1c expression and prevent diet-induced fatty liver through AMPK activation

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