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322 Although it is not clear how the deacetylase acts as a coactivator to promote anti-oxidation genes in MSC, this study shows that SIRT6 is crucial to mediate the anti-stress and anti-ageing effect of MSC

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The ESI settings were 30/10/1 for sheath/aux/sweep gas flow rates, 2.50 kV for spray voltage, 50 for S-lens RF level, 350 C for capillary temperature, and 300 C for auxiliary gas heater temperature